Site-specific inhibition of RNA polymerase II preinitiation complex assembly by human cytomegalovirus IE86 protein.

The human cytomegalovirus major immediate-early gene encodes several protein isoforms which autoregulate the major immediate-early promoter (MIEP). One of these isoforms, the IE86 protein (UL122, IE2), is a DNA-binding protein that represses the MIEP through its cognate recognition sequence (designa...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Wu, J, Jupp, R, Stenberg, R M, Nelson, J A, Ghazal, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238221/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8230474/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.7547-7555.1993
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