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Site-specific inhibition of RNA polymerase II preinitiation complex assembly by human cytomegalovirus IE86 protein.

The human cytomegalovirus major immediate-early gene encodes several protein isoforms which autoregulate the major immediate-early promoter (MIEP). One of these isoforms, the IE86 protein (UL122, IE2), is a DNA-binding protein that represses the MIEP through its cognate recognition sequence (designa...

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Bibliographic Details
Main Authors: Wu, J, Jupp, R, Stenberg, R M, Nelson, J A, Ghazal, P
Format: Artigo
Language:Inglês
Published: 1993
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC238221/
https://ncbi.nlm.nih.gov/pubmed/8230474
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