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Poliovirus capsid proteins derived from P1 precursors with glutamine-valine cleavage sites have defects in assembly and RNA encapsidation.

Assembly of poliovirus virions requires proteolytic cleavage of the P1 capsid precursor polyprotein between two separate glutamine-glycine (QG) amino acid pairs by the viral protease 3CD. In this study, we have investigated the effects on P1 polyprotein processing and subsequent assembly of processe...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ansardi, D C, Morrow, C D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238192/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8230452/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.7284-7297.1993
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