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Inhibition of Rev activity and human immunodeficiency virus type 1 replication by antisense oligodeoxynucleotide phosphorothioate analogs directed against the Rev-responsive element.

The interaction between the Rev protein of human immunodeficiency virus type 1 and its highly structured and conserved RNA target, the Rev-responsive element, is required for virus replication. We demonstrate that antisense oligodeoxynucleotide phosphorothioate analogs directed against the Rev-respo...

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Udgivet i:J Virol
Principais autores: Li, G, Lisziewicz, J, Sun, D, Zon, G, Daefler, S, Wong-Staal, F, Gallo, R C, Klotman, M E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238137/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8411393/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.11.6882-6888.1993
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