Mutagenesis of the yellow fever virus NS2B protein: effects on proteolytic processing, NS2B-NS3 complex formation, and viral replication.

To study the role of specific regions of the yellow fever virus NS2B protein in proteolytic processing and association with the NS3 proteinase domain, a series of mutations were created in the hydrophobic regions and in a central conserved hydrophilic region proposed as a domain important for NS2B f...

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Bibliographic Details
Published in:J Virol
Main Authors: Chambers, T J, Nestorowicz, A, Amberg, S M, Rice, C M
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238121/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8411382/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.11.6797-6807.1993
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