Replication of a macrophage-tropic strain of human immunodeficiency virus type 1 (HIV-1) in a hybrid cell line, CEMx174, suggests that cellular accessory molecules are required for HIV-1 entry.

To investigate the mechanism underlying one aspect of the cellular tropism of human immunodeficiency virus type 1 (HIV-1), we used a macrophage-tropic isolate, 89.6, and screened its ability to infect a number of continuous cell lines. HIV-1 (89.6) was able to replicate robustly in a T-cell/B-cell h...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Stefano, K A, Collman, R, Kolson, D, Hoxie, J, Nathanson, N, Gonzalez-Scarano, F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238110/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8411372/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.11.6707-6715.1993
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