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Distal enhancer regulation by promoter derepression in topologically constrained DNA in vitro

Long-range promoter–enhancer interactions are a crucial regulatory feature of many eukaryotic genes yet little is known about the mechanisms involved. Using cloned chicken β(A)-globin genes, either individually or within the natural chromosomal locus, enhancer-dependent transcription is achieved in...

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Detalhes bibliográficos
Main Authors: Barton, Michelle Craig, Madani, Navid, Emerson, Beverly M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23808/
https://ncbi.nlm.nih.gov/pubmed/9207078
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