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Probing the structure of the V2 domain of human immunodeficiency virus type 1 surface glycoprotein gp120 with a panel of eight monoclonal antibodies: human immune response to the V1 and V2 domains.

We have analyzed a panel of eight murine monoclonal antibodies (MAbs) that depend on the V2 domain for binding to human immunodeficiency virus type 1 (HIV-1) gp120. Each MAb is sensitive to amino acid changes within V2, and some are affected by substitutions elsewhere. With one exception, the MAbs w...

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Udgivet i:J Virol
Principais autores: Moore, J P, Sattentau, Q J, Yoshiyama, H, Thali, M, Charles, M, Sullivan, N, Poon, S W, Fung, M S, Traincard, F, Pinkus, M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238036/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7690418/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.10.6136-6151.1993
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