Infection of peripancreatic lymph nodes but not islets precedes Kilham rat virus-induced diabetes in BB/Wor rats.

A parvovirus serologically identified as Kilham rat virus (KRV) reproducibly induces acute type I diabetes in diabetes-resistant BB/Wor rats. The tissue tropism of KRV was investigated by in situ hybridization with a digoxigenin-labelled plasmid DNA probe containing approximately 1.6 kb of the genom...

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Pubblicato in:	J Virol
Autori principali:	Brown, D W, Welsh, R M, Like, A A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238006/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8371347/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.10.5873-5878.1993
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