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Mutation of large T-antigen-binding site A, but not site B or C, eliminates stalling by RNA polymerase II in the intergenic region of polyomavirus DNA.

During transcription of the late strand of polyomavirus DNA, RNA polymerase II stalls and accumulates nearby the binding sites on viral DNA recognized by polyomavirus large T antigen. Stalling by RNA polymerases is eliminated when thermolabile large T antigen is inactivated by using a temperature-se...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Bertin, J, Sunstrom, N A, Acheson, N H
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237994/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8396655/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.10.5766-5775.1993
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