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High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif

The phosphotyrosine-binding (PTB) domain is a recently identified protein module that has been characterized as binding to phosphopeptides containing an NPXpY motif (X = any amino acid). We describe here a novel peptide sequence recognized by the PTB domain from Drosophila Numb (dNumb), a protein in...

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Sparad:
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Li, Shun-Cheng, Songyang, Zhou, Vincent, Sébastien J. F., Zwahlen, Catherine, Wiley, Sandra, Cantley, Lewis, Kay, Lewis E., Forman-Kay, Julie, Pawson, Tony
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 1997
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23792/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207069/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.14.7204
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