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The hypervariable C-terminal tail of the Sendai paramyxovirus nucleocapsid protein is required for template function but not for RNA encapsidation.

The paramyxovirus nucleocapsid proteins (NPs) are relatively well conserved, except for the C-terminal 20% (or ca. 100 amino acids), referred to as the tail. We have examined whether this hypervariable tail is required for genome synthesis, both in vitro, where synthesis is predominantly from the in...

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Udgivet i:J Virol
Principais autores: Curran, J, Homann, H, Buchholz, C, Rochat, S, Neubert, W, Kolakofsky, D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237806/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8389932/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.7.4358-4364.1993
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