Genomic organization and expression of Tpl-2 in normal cells and Moloney murine leukemia virus-induced rat T-cell lymphomas: activation by provirus insertion.

Tpl-2 is a gene encoding a protein kinase which is primarily expressed in normal spleen, thymus, and lung tissue and is activated by provirus insertion in Moloney murine leukemia virus-induced T-cell lymphomas during the late stages of oncogenesis. Tpl-2 is composed of eight exons and spans a 35-kb...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Makris, A, Patriotis, C, Bear, S E, Tsichlis, P N
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237798/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8510223/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.7.4283-4289.1993
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