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Functional analysis of Leishmania major cyclophilin
A potent immunosuppressive drug cyclosporin A (CsA) is known to inhibit human cell infection by the pathogenic protozoan parasite Leishmania major both in vitro and in vivo. The proposed mechanism of action involves CsA binding to Leishmania major-expressed cyclophilin and subsequent down-regulation...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Australian Society for Parasitology Inc. Published by Elsevier Ltd.
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2377454/ https://ncbi.nlm.nih.gov/pubmed/17991468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2007.10.001 |
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