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Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants.

Delivery of genes via receptor-mediated endocytosis is severely limited by the poor exit of endocytosed DNA from the endosome. A large enhancement in delivery efficiency has been obtained by including human adenovirus particles in the delivery system. This enhancement is probably a function of the n...

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Bibliographic Details
Published in:J Virol
Main Authors: Cotten, M, Wagner, E, Zatloukal, K, Birnstiel, M L
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237742/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8099627/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.7.3777-3785.1993
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