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A direct demonstration of recombination between an injected virus and endogenous viral sequences, resulting in the generation of mink cell focus-inducing viruses in AKR mice.

We analyzed viral recombination events that occur during the preleukemic period in AKR mice. We tagged a molecular chimera between the nonleukemogenic virus Akv and the leukemogenic mink cell focus-inducing (MCF) virus MCF 247 with an amber suppressor tRNA gene, supF. We injected the supF-tagged chi...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: DiFronzo, N L, Holland, C A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1993
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237740/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8510205/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.7.3763-3770.1993
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