Hybrid hepatitis B virus nucleocapsid bearing an immunodominant region from hepatitis B virus surface antigen.

A hepatitis B core antigen (HBcAg) gene bearing the 39-amino-acid-long domain A of hepatitis B surface antigen (HBsAg) within the HBcAg immunodominant loop has been constructed and expressed in Escherichia coli. Chimeric capsids demonstrated HBs but not HBc antigenicity and elicited in mice B-cell a...

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Main Authors: Borisova, G, Arya, B, Dislers, A, Borschukova, O, Tsibinogin, V, Skrastina, D, Eldarov, M A, Pumpens, P, Skryabin, K G, Grens, E
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC237728/
https://ncbi.nlm.nih.gov/pubmed/7684473
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