Effects of long-term low-dose oxygen supplementation on the epithelial function, collagen metabolism and interstitial fibrogenesis in the guinea pig lung

BACKGROUND: The patient population receiving long-term oxygen therapy has increased with the rising morbidity of COPD. Although high-dose oxygen induces pulmonary edema and interstitial fibrosis, potential lung injury caused by long-term exposure to low-dose oxygen has not been fully analyzed. This...

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Detalhes bibliográficos
Main Authors: Aoki, Takuya, Yamasawa, Fumihiro, Kawashiro, Takeo, Shibata, Tetsuichi, Ishizaka, Akitoshi, Urano, Tetsuya, Okada, Yasumasa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377243/
https://ncbi.nlm.nih.gov/pubmed/18439301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-37
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