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The parathyroid hormone-related protein receptor is expressed in breast cancer bone metastases and promotes autocrine proliferation in breast carcinoma cells

Overproduction of parathyroid hormone-related protein (PTHRP) occurs in a high proportion of primary breast cancers (PBC) and is strongly implicated in their metastatic spread to bone. Although the PTHRP-receptor (PTHRP-R) is often coexpressed with PTHRP in PBC, its role in regulating breast cancer...

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Detalhes bibliográficos
Main Authors: Hoey, R P, Sanderson, C, Iddon, J, Brady, G, Bundred, N J, Anderson, N G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377170/
https://ncbi.nlm.nih.gov/pubmed/12592371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600757
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