Quinazoline-based α1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-β signalling and IκBα induction

Previous studies documented the ability of quinazoline-based α1-adrenoceptor antagonists to induce apoptosis in prostate cancer cells via an α1-adrenoceptor-independent mechanism. In this study we investigated the molecular events initiating this apoptotic effect. Since transforming growth factor-β1...

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Hlavní autoři: Partin, J V, Anglin, I E, Kyprianou, N
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2003
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377124/
https://ncbi.nlm.nih.gov/pubmed/12771931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600961
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