Adaptive intrapatient dose escalation of cisplatin in combination with low-dose vp16 in patients with nonsmall cell lung cancer

The objective of this phase II and pharmacologic study was to explore the feasibility, toxicity and activity of adaptive intrapatient dose escalation of cisplatin in a dose-intensive weekly schedule using predefined levels of exposure, with the ultimate aim to improve the antitumour activity of the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schellens, J H M, Planting, ASTh, van Zandwijk, N, Ma, J, Maliepaard, M, van der Burg, M E L, de Boer-Dennert, M, Brouwer, E, van der Gaast, A, van den Bent, M J, Verweij, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2003
Schlagworte:
Clinical
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377089/
https://ncbi.nlm.nih.gov/pubmed/12644815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600794
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