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Chemokine receptor CCR2 is expressed by human multiple myeloma cells and mediates migration to bone marrow stromal cell-produced monocyte chemotactic proteins MCP-1, -2 and -3

The restricted bone marrow (BM) localisation of multiple myeloma (MM) cells most likely results from a specific homing influenced by chemotactic factors, combined with the proper signals for growth and survival provided by the BM microenvironment. In analogy to the migration and homing of normal lym...

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Bibliografiske detaljer
Main Authors: Broek, I Vande, Asosingh, K, Vanderkerken, K, Straetmans, N, Van Camp, B, Van Riet, I
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377079/
https://ncbi.nlm.nih.gov/pubmed/12644822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600833
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