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Role of cystine transport in intracellular glutathione level and cisplatin resistance in human ovarian cancer cell lines

Transport system x(c)(−) is a member of plasma membrane heterodimeric amino-acid transporters and consists of two protein components, xCT and 4F2hc. This system mediates cystine entry coupled with the exodus of intracellular glutamate and regulates the intracellular glutathione (GSH) levels in most...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Okuno, S, Sato, H, Kuriyama-Matsumura, K, Tamba, M, Wang, H, Sohda, S, Hamada, H, Yoshikawa, H, Kondo, T, Bannai, S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377069/
https://ncbi.nlm.nih.gov/pubmed/12644836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600786
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