Irinotecan plus leucovorin-modulated 5-fluorouracil I.V. bolus every other week may be a suitable therapeutic option also for elderly patients with metastatic colorectal carcinoma

The aim of this study was to assess the safety and efficacy of biweekly irinotecan plus leucovorin-modulated 5-fluorouracil i.v. bolus in metastatic colorectal carcinoma according to the age of patients. For this purpose, we have analysed 108 patients randomly allocated to receive irinotecan 200 mg ...

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Hlavní autoři: Comella, P, Farris, A, Lorusso, V, Palmeri, S, Maiorino, L, Lucia, L De, Buzzi, F, Mancarella, S, Vita, F De, Gambardella, A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2003
Témata:
Clinical
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376956/
https://ncbi.nlm.nih.gov/pubmed/12966414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601214
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