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Telomerase activity, apoptosis and cell cycle progression in ataxia telangiectasia lymphocytes expressing TCL1

Individuals affected by ataxia telangiectasia (AT) have a marked susceptibility to cancer. Ataxia telangiectasia cells, in addition to defects in cell cycle checkpoints, show dysfunction of apoptosis and of telomeres, which are both thought to have a role in the progression of malignancy. In 1–5% of...

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Detalhes bibliográficos
Main Authors: Gabellini, C, Antonelli, A, Petrinelli, P, Biroccio, A, Marcucci, L, Nigro, G, Russo, G, Zupi, G, Elli, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376941/
https://ncbi.nlm.nih.gov/pubmed/12966431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601213
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