Association of microsomal epoxide hydrolase polymorphisms and lung cancer risk

Microsomal epoxide hydrolase (mEH) plays a dual role in the detoxification and activation of tobacco procarcinogens. Two polymorphisms affecting enzyme activity have been described in the exons 3 and 4 of the mEH gene, which result in the substitution of amino acids histidine to tyrosine at residue...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gsur, A, Zidek, T, Schnattinger, K, Feik, E, Haidinger, G, Hollaus, P, Mohn-Staudner, A, Armbruster, C, Madersbacher, S, Schatzl, G, Trieb, K, Vutuc, C, Micksche, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2003
Schlagworte:
Genetics and Genomics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376930/
https://ncbi.nlm.nih.gov/pubmed/12915882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601142
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