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Phase II trial of irinotecan plus docetaxel in cisplatin-pretreated relapsed or refractory oesophageal cancer

This phase II trial assessed the toxicity and efficacy of irinotecan plus docetaxel in cisplatin-pretreated oesophageal cancer. Irinotecan 160 mg m(−2) plus docetaxel 65 mg m(−2) once every 3 weeks led to severe myelosuppression in four patients, all of whom experienced neutropenic fever. After amen...

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Detalhes bibliográficos
Main Authors: Lordick, F, von Schilling, C, Bernhard, H, Hennig, M, Bredenkamp, R, Peschel, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376928/
https://ncbi.nlm.nih.gov/pubmed/12915869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601168
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