DNA topoisomerase IIα expression and the response toprimary chemotherapy in breast cancer

The α isoform of Topoisomerase IIα (Topo IIα) is a proliferation marker as well as a target for several chemotherapeutic agents such as anthracyclines. In vitro studies have demonstrated the relationship between the Topo IIα expression level and chemosensitivity of target cancer cells. To verify thi...

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Главные авторы: MacGrogan, G, Rudolph, P, Mascarel, I de, Mauriac, L, Durand, M, Avril, A, Dilhuydy, J M, Robert, J, Mathoulin-Pélissier, S, Picot, V, Floquet, A, Sierankowski, G, Coindre, J M
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2003
Предметы:
Molecular and Cellular Pathology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376904/
https://ncbi.nlm.nih.gov/pubmed/12915875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601185
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