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Top-Down and Bottom-up Mass Spectrometric Characterization of Human Myoglobin-Centered Free Radicals Induced by Oxidative Damage

In an effort to determine the utility of top down mass spectrometric methodologies for the characterization of protein radical adducts, top down approaches were investigated and compared to the traditional bottom up approaches. Specifically, the nature of the radicals on human myoglobin induced by t...

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Detalhes bibliográficos
Main Authors: Deterding, Leesa J., Bhattacharjee, Suchandra, Ramirez, Dario C., Mason, Ronald P., Tomer, Kenneth B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376835/
https://ncbi.nlm.nih.gov/pubmed/17637042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac070935z
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