Transformation induced by Ewing's sarcoma associated EWS/FLI-1 is suppressed by KRAB/FLI-1

Ewing's sarcoma is a childhood bone tumour with poor prognosis, most commonly associated with a t(11;22)(q24;q12) reciprocal translocation that fuses the EWS and FLI-1 genes, resulting in the production of an aberrant chimeric transcription factor EWS/FLI-1. To elucidate the mechanisms by which...

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Bibliographic Details
Main Authors: Chan, D, Wilson, T J, Xu, D, Cowdery, H E, Sanij, E, Hertzog, P J, Kola, I
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2003
Subjects:
Molecular and Cellular Pathology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376791/
https://ncbi.nlm.nih.gov/pubmed/12556973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600669
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