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Crystallization and preliminary crystallographic studies of Hyp-1, a St John’s wort protein implicated in the biosynthesis of hypericin

According to a debated hypothesis, the biosynthesis from emodin of the medicinally important natural compound hypericin is catalyzed in St John’s wort (Hypericum perforatum) by the phenolic oxidative-coupling protein Hyp-1. Recombinant St John’s wort Hyp-1 has been overexpressed in Escherichia coli...

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Main Authors: Fernandes, Humberto, Konieczna, Malgorzata, Kolodziejczyk, Robert, Bujacz, Grzegorz, Sikorski, Michal, Jaskolski, Mariusz
Formato: Artigo
Idioma:Inglês
Publicado: International Union of Crystallography 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376394/
https://ncbi.nlm.nih.gov/pubmed/18453712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108009111
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