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Endothelin-receptor antagonists are proapoptotic and antiproliferative in human colon cancer cells
Endothelin (ET)-1 can act as an autocrine/paracrine growth factor or an antiapoptotic factor in human cancers. To study the role of ET-1 in human colon cancer, proliferation and apoptosis of colon carcinoma cells was investigated using human HT-29 and SW480 colon carcinoma cells. ET-1 was secreted b...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2376352/ https://ncbi.nlm.nih.gov/pubmed/12618891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600810 |
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