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Penetration of capecitabine and its metabolites into malignant and healthy tissues of patients with advanced breast cancer
Capecitabine is an oral prodrug of 5-fluorouracil (FU). Since FU concentrations achieved in malignant lesions are an important determinant of efficacy, we investigated the intratumoral transcapillary transfer of capecitabine and its metabolites in vivo. A total of 10 patients with skin metastases fr...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2376334/ https://ncbi.nlm.nih.gov/pubmed/12618890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600809 |
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