A Novel GDP-dependent Pyruvate Kinase Isozyme from Toxoplasma gondii Localizes to Both the Apicoplast and the Mitochondrion

We previously reported a cytosolic pyruvate kinase (EC 2.7.1.40) from Toxoplasma gondii (TgPyKI) that differs from most eukaryotic pyruvate kinases in being regulated by glucose 6-phosphate rather than fructose 1,6-diphosphate. Another putative pyruvate kinase (TgPyKII) was identified from parasite...

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Detalhes bibliográficos
Main Authors: Saito, Tomoya, Nishi, Manami, Lim, Muoy I., Wu, Bo, Maeda, Takuya, Hashimoto, Hisayuki, Takeuchi, Tsutomu, Roos, David S., Asai, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Enzyme Catalysis and Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376232/
https://ncbi.nlm.nih.gov/pubmed/18326043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709015200
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