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Secretion of soluble complement inhibitors factor H and factor H-like protein (FHL-1) by ovarian tumour cells

We observed that the soluble complement regulators factor H and factor H-like protein were abundantly present in ascites samples as well as in primary tumours of patients with ovarian cancer. RT–PCR and immunoblotting analyses showed that the two complement inhibitors were constitutively produced by...

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Detalhes bibliográficos
Main Authors: Junnikkala, S, Hakulinen, J, Jarva, H, Manuelian, T, Bjørge, L, Bützow, R, Zipfel, P F, Meri, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376183/
https://ncbi.nlm.nih.gov/pubmed/12402151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600614
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