The NF-kappa B binding site is necessary for efficient replication of simian immunodeficiency virus of macaques in primary macrophages but not in T cells in vitro.

We demonstrate here that the nuclear factor-kappa B (NF-kappa B) binding site in the simian immunodeficiency virus (SIVmac) long terminal repeat is essential for efficient virus replication in primary alveolar macrophages but dispensable for efficient replication in primary T cells. Mutation of the...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Bellas, R E, Hopkins, N, Li, Y
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237617/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8474179/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.5.2908-2913.1993
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