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Binding of TGF-β1 latency-associated peptide (LAP) to αvβ6 integrin modulates behaviour of squamous carcinoma cells

The integrin αvβ6 is not detectable on normal keratinocytes in vivo but expression is increased significantly in oral squamous cell carcinoma where this heterodimer has been shown to play a role in cell migration, invasion and protease expression. Although regarded initially as a fibronectin recepto...

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Detalhes bibliográficos
Main Authors: Thomas, G J, Hart, I R, Speight, P M, Marshall, J F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376166/
https://ncbi.nlm.nih.gov/pubmed/12373600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600545
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