Differential diagnosis between chronic pancreatitis and pancreatic cancer: value of the detection of KRAS2 mutations in circulating DNA

KRAS2 mutations in codon 12 have been detected in about 80% of pancreatic cancers. The aim of this study was to evaluate the value of KRAS2 mutations detection in circulating deoxyribo nucleic acid to differentiate pancreatic cancer from chronic pancreatitis. Circulating deoxyribo nucleic acid was i...

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Hlavní autoři: Maire, F, Micard, S, Hammel, P, Voitot, H, Lévy, P, Cugnenc, P-H, Ruszniewski, P, Puig, P Laurent
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2002
Témata:
Molecular and Cellular Pathology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376157/
https://ncbi.nlm.nih.gov/pubmed/12189555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600475
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