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High-resolution genome-wide allelotype analysis identifies loss of chromosome 14q as a recurrent genetic alteration in astrocytic tumours

Diffusely infiltrative astrocytic tumours are the most common neoplasms in the human brain. To localise putative tumour suppressor loci that are involved in low-grade astrocytomas, we performed high-resolution genome-wide allelotype analysis on 17 fibrillary astrocytomas. Non-random allelic losses w...

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Detalhes bibliográficos
Main Authors: Hu, J, Pang, JC-s, Tong, CY-k, Lau, B, Yin, X-l, Poon, W-S, Jiang, C-C, Zhou, L-F, Ng, H-K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376105/
https://ncbi.nlm.nih.gov/pubmed/12107846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600430
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