Assembly-defective point mutants of the human immunodeficiency virus type 1 Gag precursor phenotypically expressed in recombinant baculovirus-infected cells.

Two substitution mutants of the human immunodeficiency virus type 1 gag gene product were isolated after nitrous acid mutagenesis of a recombinant baculovirus expressing a non-N-myristylated, p6-deleted Gag precursor (Pr49). Both mutants failed to assemble intracellular Gag virus-like particles, as...

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Bibliographic Details
Published in:J Virol
Main Authors: Hong, S S, Boulanger, P
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237603/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8474175/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.5.2787-2798.1993
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