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The simulation of stress fibre and focal adhesion development in cells on patterned substrates

The remodelling of the cytoskeleton and focal adhesion (FA) distributions for cells on substrates with micro-patterned ligand patches is investigated using a bio-chemo-mechanical model. We investigate the effect of ligand pattern shape on the cytoskeletal arrangements and FA distributions for cells...

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Autores principales: Pathak, Amit, Deshpande, Vikram S, McMeeking, Robert M, Evans, Anthony G
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375958/
https://ncbi.nlm.nih.gov/pubmed/17939980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2007.1182
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