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Complement-mediated binding of naturally glycosylated and glycosylation-modified human immunodeficiency virus type 1 to human CR2 (CD21).

Particulate glycoproteins lacking sialic acid, such as desialylated enveloped viruses, readily activate complement through the alternative pathway. Human immunodeficiency virus type 1 (HIV-1) contains two heavily glycosylated and partially sialylated envelope glycoproteins: a surface gp120 and a tra...

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Main Authors: Montefiori, D C, Stewart, K, Ahearn, J M, Zhou, J
格式: Artigo
語言:Inglês
出版: 1993
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC237592/
https://ncbi.nlm.nih.gov/pubmed/8474169
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