A Friend virus mutant that overcomes Fv-2rr host resistance encodes a small glycoprotein that dimerizes, is processed to cell surfaces, and specifically activates erythropoietin receptors.

The env gene of Friend spleen focus-forming virus (SFFV) encodes a membrane glycoprotein (gp55) that is inefficiently (3 to 5%) processed from the rough endoplasmic reticulum to form a larger dimeric plasma membrane derivative (gp55p). Moreover, the SFFV env glycoprotein associates with erythropoiet...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kozak, S L, Hoatlin, M E, Ferro, F E, Majumdar, M K, Geib, R W, Fox, M T, Kabat, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237582/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8474164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.5.2611-2620.1993
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