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Mutations in the putative calcium-binding domain of polyomavirus VP1 affect capsid assembly.

Calcium ions appear to play a major role in maintaining the structural integrity of the polyomavirus and are likely involved in the processes of viral uncoating and assembly. Previous studies demonstrated that a VP1 fragment extending from Pro-232 to Asp-364 has calcium-binding capabilities. This fr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Haynes, J I, Chang, D, Consigli, R A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC237567/
https://ncbi.nlm.nih.gov/pubmed/8386264
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