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NKCC1 cotransporter inactivation underlies embryonic development of chloride-mediated inhibition in mouse spinal motoneuron

Early in development, GABA and glycine exert excitatory action that turns to inhibition due to modification of the chloride equilibrium potential (E(Cl)) controlled by the KCC2 and NKCC1 transporters. This switch is thought to be due to a late expression of KCC2 associated with a NKCC1 down-regulati...

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Bibliografski detalji
Glavni autori: Delpy, Alain, Allain, Anne-Emilie, Meyrand, Pierre, Branchereau, Pascal
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375629/
https://ncbi.nlm.nih.gov/pubmed/18096599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.146993
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