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Switch to Ca(2+)-permeable AMPA and reduced NR2B NMDA receptor-mediated neurotransmission at dorsal horn nociceptive synapses during inflammatory pain in the rat
Glutamate receptor response properties of nociceptive synapses on neurokinin 1 receptor positive (NK1R(+)) lamina I neurons were determined 3 days after induction of chronic peripheral inflammation with Freund's Complete Adjuvant (CFA). A significant increase in the AMPAR/NMDAR ratio was found...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science Inc
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375596/ https://ncbi.nlm.nih.gov/pubmed/18033811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.145581 |
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