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Design of compounds that increase the absorption of polar molecules

Hydrophilic drugs are often poorly absorbed when administered orally. There has been considerable interest in the possibility of using absorption enhancers to promote absorption of polar molecules across membrane surfaces. The bile acids are one of the most widely investigated classes of absorption...

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Detalhes bibliográficos
Main Authors: Bowe, Caryn Lang, Mokhtarzadeh, Leila, Venkatesan, Pushpa, Babu, Suresh, Axelrod, Helena R., Sofia, Michael J., Kakarla, Ramesh, Chan, Tin Yau, Kim, Jae Seung, Lee, Hye J., Amidon, Gordon L., Choe, Sally Y., Walker, Suzanne, Kahne, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23755/
https://ncbi.nlm.nih.gov/pubmed/9342389
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