The human gamma interferon receptor accessory factor encoded by chromosome 21 transduces the signal for the induction of 2',5'-oligoadenylate-synthetase, resistance to virus cytopathic effect, and major histocompatibility complex class I antigens.

Mouse fibroblasts, and human-mouse hybrid fibroblasts carrying only human chromosome 21, were transfected with cDNA encoding full-length human gamma interferon (IFN-gamma) receptor or chimeric IFN-gamma receptor (extracellular domain of the human receptor; transmembrane and intracellular domains of...

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Vydáno v:	J Virol
Hlavní autoři:	Kalina, U, Ozmen, L, Di Padova, K, Gentz, R, Garotta, G
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1993
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237547/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8437239/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.3.1702-1706.1993
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