Evaluation of HER-2/neu gene amplification and protein expression in non-small cell lung carcinomas

HER-2/neu gene amplification and cell surface overexpression are important factors in breast cancer for prognosis and prediction of sensitivity to anti-HER-2/neu monoclonal antibody therapy. In lung cancer, the clinical significance of HER-2/neu expression is currently under evaluation. We investiga...

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Autors principals: Hirsch, F R, Varella-Garcia, M, Franklin, W A, Veve, R, Chen, L, Helfrich, B, Zeng, C, Baron, A, Bunn, P A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2002
Matèries:
Molecular and Cellular Pathology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375387/
https://ncbi.nlm.nih.gov/pubmed/11986780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600286
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