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Is there a dose response relationship for clodronate in the treatment of tumour induced hypercalcaemia?

Eighty-six patients with tumour induced hypercalcaemia were randomised to 600, 900, 1200 or 1500 mg of intravenous clodronate, according to post hydration serum calcium levels. Sixty-seven were evaluable for response. The overall response rate was 49.3% (95% CI: 36.8–61.8) with no significant differ...

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Detalhes bibliográficos
Main Authors: Shah, S, Hardy, J, Rees, E, Ling, J, Gwilliam, B, Davis, C, Broadley, K, A'Hern, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375352/
https://ncbi.nlm.nih.gov/pubmed/11953878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600249
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