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Prognostic value of CCND1 gene status in sporadic breast tumours, as determined by real-time quantitative PCR assays

The CCND1 gene, a key cell-cycle regulator, is often altered in breast cancer, but the mechanisms underlying CCND1 dysregulation and the clinical significance of CCND1 status are unclear. We used real-time quantitative PCR and RT–PCR assays based on fluorescent TaqMan methodology to quantify CCND1 g...

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Main Authors: Bièche, I, Olivi, M, Noguès, C, Vidaud, M, Lidereau, R
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375286/
https://ncbi.nlm.nih.gov/pubmed/11870541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600109
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